Visit with Xenobiotic transporters Antioxidant reply, 140 Anuria, 180 Apaf-1 role in apoptosome, 113 repressing through Hsp70, 139 AP endonucleases, duty in ground excision service, 238 Apoptosis delimitation and determining, 112 induction via DNA damage, 238 instrinsic pathway, 115 role in toper cardiac myopathy, 279 duty of caspases, 113 Aristolochic acid enzymatic nitroreduction, 250 role in Balkans endemic nephropathy, 248 Pungent amines, 306 historical content, 11 Arsenic, 7, 9 presence in tobacco smoke, 298 Arylhydrocarbon receptor (AhR) inducing ligands, 132 structural features, 131 toxicity receptor original, 94 Aryl hydrocarbon receptor nuclear translocator (ARNT), 131 Asbestos asbestosis in exposed workers, 254 inconsistency of corporeal forms and woman usage, 253 true moment, 11 ATF6 activation pathway, 145 function in ER underscore return, 145 ATF4, position in ER bring into prominence response, 145 Azidothymidine (AZT), hepatotoxic covert, 166 B Centre excision set right (BER), 238 Bcl-2, role in apoptosis, 113 Benzene, alliance with leukemia, 74 Benzoquinone, 74 Biliary excretion, consequence of aggregate, 82 Bioactivation contributions to carcinogen activation, 231 acutance and toxicological roles, 95 metabolic activation of NNN and NNK, 304 situation in spirits toxicity, 265 position in benzene toxicity, 74 task in chloroform nephrotoxicity, 183 situation in developmental toxicity, 195 capacity in paracetamol hepatotoxicity, 164 role in the genotoxicity of pol